|
Symbol Name ID |
Fanca
Fanconi anemia, complementation group A MGI:1341823 |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypogonadism |
Hypergonadotropic hypogonadism |
Hypospadias |
Abnormal preputium morphology |
Abnormal testis morphology |
Absent testis |
Cryptorchidism |
Dysgerminoma |
Ovarian carcinoma |
Ovarian papillary adenocarcinoma |
Abnormality of the uterus |
Cervix cancer |
Bicornuate uterus |
Azoospermia |
Decreased fertility in males |
Male infertility |
| Disease(s) Associated with FANCA | ||||||||||||||||
| cervical cancer | ||||||||||||||||
| Fanconi anemia | ||||||||||||||||
| Fanconi anemia complementation group A | ||||||||||||||||
| ovarian cancer | ||||||||||||||||
| pancreatic cancer |
| Mouse Phenotypes | ovary hemorrhage |
decreased germ cell number |
increased male germ cell apoptosis |
abnormal ovary morphology |
decreased mature ovarian follicle number |
absent mature ovarian follicles |
small ovary |
ovary hypoplasia |
ovary cyst |
small seminiferous tubules |
seminiferous tubule degeneration |
increased Leydig cell number |
decreased testis weight |
small testis |
early reproductive senescence |
abnormal male meiosis |
abnormal spermatogenesis |
small gonad |
reduced female fertility |
decreased litter size |
reduced male fertility |
|
| Availability | Mouse Genotype | |||||||||||||||||||||
| Fancatm1.1Wong/Fancatm1.1Wong | ! | ! | ||||||||||||||||||||
| Fancatm1Faw/Fancatm1Faw | ||||||||||||||||||||||
| Fancatm1Wong/Fancatm1Wong | ! | |||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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